A second successive playoff defeat with the Dorados will inevitably lead to speculation about how long Maradona, took over at the club from northern Mexico in September 2018, will stick around.
The colourful former Argentina captain threatened to quit only last month, alleging that referees did not give his side fair treatment because he was in charge.
A World Cup winner in 1986 and widely considered one of the greatest players of all time, Maradona has had a chequered coaching career and rarely stayed long at one club.
He has also suffered from regular health problems, most recently earlier this year when he spent several days in hospital with internal bleeding in his stomach.
Diego Maradona has experienced the disappointment of missing out on promotion as a coach for the second year in a row after his Mexican club Sinaloa Dorados lost a nail-biting second division playoff on Sunday.
The Dorados lost 1-0 after extra time in the second leg at Atletico San Luis, a result which left the aggregate score at 2-1 and handed the Clausura title, as well as promotion, to the home side.